CD63

CD63, Monoclonal, IgG1, Host: Mouse, APC

Clone: TEA3/18.

Conjugate: APC.

Immunogen: Tissue / cell preparation (Human cytochrome B enriched cells).

Storage Buffer: The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3).

CD63 is a 53 kD, type III lysosomal glycoprotein, expressed on activated platelets, monocytes and macrophages. CD63 contains four hydrophobic transmembrane domains with a major extracellular region of 95 amino acids between transmembrane segments 3 and 4. The COOH-terminal sequence SGYEVM functions as a lysosomal targeting sequence. This molecule is also referred highly to as LIMP, gp55,melanoma-associated antigen ME491, Pltgp40, LAMP-3 and is a member of the tetraspan transmembrane 4 superfamily (TM4SF). It is also widely expressed on surface and in the cytoplasm of various hematopoietic (monocytes, macrophages) and non-hematopoietic cells (endothelium, fibroblasts, osteoclasts, smooth muscle). Its cellular function has not been fully elucidated. Reports suggest this as a useful molecule to study platelet activation.

• Artikelnummer: IMS63A-100T
• Hersteller: Immunostep
• Hersteller Artikelnummer: 63A-100T
• Green Labware: Nein
• Verpackungseinheit: 100 Tests
• Mengeneinheit: PAK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Flow Cytometry
• Isotyp: IgG1
• Human Gene ID: 967
• Wirt: Mouse