CD74 (B-Cell Marker)(CLIP/3127R), 1mg/mL

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Description: Recognizes a protein of ~35 kDa, identified as CD74 (Workshop IV). CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma ( ). Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Oryctolagus cuniculus (domestic rabbit)

Clone: CLIP/3127R

Entrez Gene ID: 972

Immunogen: SU-DHL-4 lymphoma cells

Verified AB Applications: Flow (verified)/IHC (FFPE) (verified)/WB (verified)

Z-Antibody Applications: Flow (verified)/IHC, FFPE (verified)/WB (verified)

• Artikelnummer: BTMBNUM3127-50
• Hersteller: Biotium
• Hersteller Artikelnummer: BNUM3127-50
• Verpackungseinheit: 50 uL
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Primate
• Klonalität: Recombinant
• Methode: Western Blotting, Flow Cytometry, Immunohistochemistry
• Isotyp: IgG
• Wirt: Rabbit
• Konjugat: Unconjugated