CD8(C8/1035), 1mg/mL

CD8(C8/1035), 1mg/mL
Artikelnummer
BTMBNUM1035-50
Verpackungseinheit
50 uL
Hersteller
Biotium

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Description: CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4 /CD8-. Anaplastic large cell lymphoma is usually CD4 and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Mus musculus (mouse)

Clone: C8/1035

Entrez Gene ID: 925

Immunogen: Recombinant full-length human CD8a protein

Verified AB Applications: Flow (surface) (verified)/IF (verified)

Z-Antibody Applications: Flow, surface (verified)/IF (verified)
Mehr Informationen
Artikelnummer BTMBNUM1035-50
Hersteller Biotium
Hersteller Artikelnummer BNUM1035-50
Green Labware Nein
Verpackungseinheit 50 uL
Mengeneinheit STK
Reaktivität Human
Klonalität Monoclonal
Methode Immunofluorescence, Flow Cytometry
Isotyp IgG1 kappa
Wirt Mouse
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