Clone Name: CEA31
Light Chain: Kappa
Application Note: IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 27
Positive Control: Colon carcinoma
Specificity/Sensitivity: Clone CEA31 has a high affinity for CEA and shows no detectable reactivity to nonspecific cross-reacting antigen (NCA), biliary glycoprotein (BGP) and human polymorphonuclear leucocytes.
Form: Liquid
Buffer (with preservative): Tris-HCl buffer, 0.2% BSA, 0.09% Sodium azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2013]
Uniprot ID: P40198
Antigen Species: Human
Immunogen: Human colon carcinoma extract
Purification: Purified IgG
Conjugation: Unconjugated
Full Name: carcinoembryonic antigen related cell adhesion molecule 3