CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), 1mg/mL

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Description: This antibody recognizes a protein of 165-170 kDa, identified as cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Oryctolagus cuniculus (domestic rabbit)

Clone: CFTR/2290R

Entrez Gene ID: 1080

Immunogen: Recombinant full-length human CFTR protein

Verified AB Applications: IHC (FFPE) (verified)

Z-Antibody Applications: IHC, FFPE (verified)

• Artikelnummer: BTMBNUM2290-50
• Hersteller: Biotium
• Hersteller Artikelnummer: BNUM2290-50
• Verpackungseinheit: 50 uL
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine)
• Klonalität: Recombinant
• Methode: Immunohistochemistry
• Isotyp: IgG
• Wirt: Rabbit
• Konjugat: Unconjugated