CHD2, GST-tag Recombinant

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Applications: Useful for protein binding assays, screening inhibitors, and selectivity profiling.

Background: The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template.

Description: Human chromodomain helicase DNA binding protein 2, or CHD2, (GenBank Accession No. NM_001271) a.a. 260-456(end), with N-terminal GST-tag, MW=49.3 kDa, expressed in an E. coli cell expression system.

Format: Aqueous buffer solution

Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol

Genbank: NM_001271

Storage Stability: At least 6 months at -80°C.

Tags: N-terminal GST-tag

Uniprot: O14647

Warnings: Avoid freeze/thaw cycles.

Biosafety Level: Not applicable (BSL-1)

References: 1. Woodage, T., et al., Proc Natl Acad Sci
USA. 1997 Oct 14;94(21):11472-7.
2. Harada, A., et al., EMBO J. 2012 May
8;31(13):2994-3007.

• Artikelnummer: BPS55005-2
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 55005-2
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK