Cholesteryl Arachidonate-d8

Formulation: A solution in methyl acetate

Formal Name: (3β)-cholest-5-en-3-ol-d8 3-[(5Z,8Z,11Z,14Z)-5,8,11,14-eicosatetraenoate]

Purity: ≥99% deuterated forms (d1-d8)

Formula Markup: C47H68D8O2

Formula Weight: 681,2

Shelf life (days): 730

Notes: Cholesteryl arachidonate-d8 is intended for use as an internal standard for the quantification of cholesteryl arachidonate (Item No. 22595) by GC- or LC-MS. Cholesteryl arachidonate is a cholesterol ester that is found in plasma and the adrenal gland.{42068} It is a component of low-density lipoprotein (LDL) and oxidation of the arachidonate moiety contributes to macrophage activation and foam cell formation in atherosclerosis.{42069} Cholesteryl arachidonate undergoes hydrolysis to release arachidonic acid during ACTH-stimulated prostaglandin synthesis in rat adrenocortical cells.{42070} Levels of cholesteryl arachidonate are increased in the bronchoalveolar lavage fluid (BALF) in pediatric cystic fibrosis patients compared to healthy controls as well as in placentas of women with chorioamnionitis.{42071,42072}

• Artikelnummer: CAY39085-50
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 39085-50
• Verpackungseinheit: 50 µg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung