CL4H6, CAS 2256087-35-9

Formulation: A solution in ethanol

Formal Name: 9-octadecenoic acid, 1,1′-[7-[4-(dipropylamino)butyl]-7-hydroxy-1,13-tridecanediyl] ester

Purity: ≥95%

Formula Markup: C59H113NO5

Formula Weight: 916,5

Shelf life (days): 730

CAS Number: 2256087-35-9

Notes: CL4H6 is an ionizable cationic amino lipid (apparent pKa = 6.35) that has been used in the generation of lipid nanoparticles (LNPs).{65433} LNPs containing CL4H6 and encapsulating Factor VII-targeting siRNA decrease hepatic levels of Factor VII in mice. Intravenous administration of LNPs containing CL4H6 and encapsulating siRNA targeting CD45 accumulate in tumor-associated macrophages and encapsulating siRNAs targeting STAT3 and HIF-1α decrease tumor volume in OS-RC-2 renal cancer mouse xenograft models.{65434}

• Artikelnummer: CAY37279-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 37279-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK
• Methode: Reinstoffe