English
CLASP2 Polyclonal Antibody, Rabbit
CLASP2 Polyclonal Antibody, Rabbit
Artikelnummer
ELSE-AB-92600-120
Verpackungseinheit
120 µl
Hersteller
Elabscience Biotechnology
Verfügbarkeit:
wird geladen...
Preis wird geladen...
Abbreviation: CLASP2
Target Synonym: CLASP2
Conjugation: Unconjugated
UNIProt ID: O75122
Background: Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN. Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human CLASP2
Dilution: WB 1:500-1:2000
Target Synonym: CLASP2
Conjugation: Unconjugated
UNIProt ID: O75122
Background: Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN. Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human CLASP2
Dilution: WB 1:500-1:2000
| Artikelnummer | ELSE-AB-92600-120 |
|---|---|
| Hersteller | Elabscience Biotechnology |
| Hersteller Artikelnummer | ELA-E-AB-92600-120 |
| Green Labware | Nein |
| Verpackungseinheit | 120 µl |
| Mengeneinheit | STK |
| Reaktivität | Human, Mouse (Murine), Rat (Rattus) |
| Klonalität | Polyclonal |
| Methode | Western Blotting |
| Isotyp | IgG |
| Wirt | Rabbit |
| Produktinformation (PDF) | Download |
| MSDS (PDF) | Download |
Verwandte Artikel
Markieren Sie die Artikel, um Sie dem Warenkorb hinzuzufügen oder
Immer für Sie da
Gernot Ensinger, M.Sc.
Laurent Haze
