CNDAC (hydrochloride), CAS 134665-72-8

Formulation: A solid

Formal Name: 4-amino-1-(2-cyano-2-deoxy-β-D-arabinofuranosyl)-2(1H)-pyrimidinone, monohydrochloride

Purity: ≥98%

Formula Markup: C10H12N4O4 • HCl

Formula Weight: 288,7

Shelf life (days): 1460

CAS Number: 134665-72-8

Notes: CNDAC is a nucleoside derivative and an active metabolite of the prodrug sapacitabine.{51747} It induces chromosomal aberrations in UV41 cells lacking DNA repair endonuclease XPF when used at a concentration of 1 µM. CNDAC is cytotoxic to BRCA1-/- UWB1.289 and BRCA2-/- PEO1 ovarian cancer cells (IC50s = 9.9 and 10.2 nM, respectively).{51748}

• Artikelnummer: CAY40672-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 40672-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK