Collagen Type IV, rat

Collagen Type IV, rat, Host: Rabbit, Polyclonal

Background: Type IV Collagen is a non-fibrillary network of different alpha-chains: alpha 1(IV) to-alpha 6(IV). It is typically found in basal membranes of different organs (e.g. skin, lens, lung, kidney). Collagens consist of a family of highly specialized glycoproteins of which at least 16 genetically distinct types are known to date. The basal unit of a collagen molecule consists of a triple-helical structure formed by 3 alpha-chains. Predominant amino acids are glycine, proline and hydroxproline. Regularly also lysines and hydroxylysines occur, which are responsible for cross-linkage and glycosylation of the protein chains. Different composition of alpha-chains and different glycosylation contribute to the high variability of collagens in different tissues and organs. Rat collagen type IV 100%; rat collagen type I, II, III and V <0.1%; rat fibronectin <0.1%; murine laminin <0.1% (RIA at 1:5000 dilution).

Positive Control: Rat skin or liver.

Immunogen: Purified collagen type IV from rodent tumour tissue.

Purification Method: Affinity purified antibody lyophilized from phosphate buffered solution; no BSA and preservative added!.

Concentration: app. 1 mg/ml.

References: 1. Kono S, Kurata T, Sato K, Omote Y, Hishikawa N, Yamashita T, Deguchi K, Abe K (2014) Neurovascular Protection by Telmisartan via Reducing Neuroinflammation in Stroke-Resistant Spontaneously Hypertensive Rat Brain after Ischemic Stroke. J Stroke Cerebrovasc Dis. 2014 Dec 19. pii: S1052-3057(14)00498-4.

UniProt: vorläufige Daten unter F1MA59_RAT.

Caution: *These antibodies are intended for in vitro research use only. They must not be used for clinical diagnostics and not for in vivo experiments in humans or animals.

• Artikelnummer: BILCO20441-0.1
• Hersteller: BioLogo
• Hersteller Artikelnummer: CO20441-0.1
• Green Labware: Nein
• Verpackungseinheit: 0,1 ml
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus)
• Klonalität: Polyclonal
• Methode: Immunofluorescence, Immunohistochemistry (paraffin), Western Blotting, ELISA, Radioimmunoassay (RIA)
• Wirt: Rabbit