CTLA4 antibody (MSVA-152R) HistoMAX™

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Clone Name: MSVA-152R

Product Description: This antibody was validated on 76 different Normal Tissues by IHC-P.

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Application Note: IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 25

Positive Control: Tonsil: A moderate strong membranous and cytoplasmic CTLA4 immunostaining should be seen in a subset of T-lymphocytes with strongest staining in follicular T-helper cells of germinal centres.

Negative Control: Tonsil: The majority of lymphocytes in germinal centres and all epithelial cells should stain negative.

Form: Liquid

Buffer (with preservative): 10mM PBS, 0.05% BSA (Please contact us for BSA and azide free format), 0.05% sodium azide.

Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]

Uniprot ID: P16410

Antigen Species: Human

Immunogen: Recombinant fragment of human CTLA4 protein

Purification: Protein A/G purified

Conjugation: Unconjugated

Full Name: cytotoxic T-lymphocyte associated protein 4

• Artikelnummer: GTX04439-S-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX04439-S-100
• Verpackungseinheit: 100 μl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG
• Human Gene ID: 1493
• Wirt: Rabbit
• Konjugat: Unconjugated