CTLA4 (CD152), Fc-fusion (IgG1) Recombinant

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Applications: Useful for studying protein binding and screening small molecular inhibitors

Description: Human secreted CTLA4 , Fc fusion protein, also known as Cytotoxic T-lymphocyte-associated protein 4 and CD152. GenBank Accession No. NM_005214, a.a. 36-162 expressed in a HEK293 cell expression system. MW = 40.3 kDa (monomer). This protein runs at a higher MW by SDS-PAGE due to glycosylation.

Endotoxin Level: <1 EU/µg

Format: Aqueous buffer solution

Formulation: 40 mM Tris, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.

Genbank: NM_005214

Storage Stability: At least 6 months at -80°C.

Tags: C-terminal Fc fusion (Human IgG1)

Uniprot: P16410

Warnings: Avoid freeze/thaw cycles. Protein may be diluted to ≥100 µg/ml in PBS + glycerol and stored at -80°C.

Biosafety Level: Not applicable (BSL-1)

References: 1. Dilek, N., et al., PLOS ONE. 2013 Dec. 23: DOI: 10.1317.
2. Leach, D.R., et al., Science. 1996; 271(5256):1734-1736.

• Artikelnummer: BPS71149-1
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 71149-1
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK