Cytokeratin 13 (Non-Keratinized Squamous Epithelial Marker)(KRT13/2213), 1mg/mL

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Description: Cytokeratin 13 (KRT13) is the major acidic keratin, which together with KRT4, its basic partner, is expressed in the suprabasal layers of non-cornified stratified epithelia including tongue mucosa, esophagus, anal canal epithelium, tracheal epithelium, uterine cervix, and urothelium. Defects in the KRT13 gene are a cause of white sponge nevus of cannon (WSN), a rare autosomal dominant disorder, which predominantly affects non-cornified stratified squamous epithelia and is characterized by the presence of soft, white and spongy plaques in the oral mucosa. KRT13 has been used as a marker for non-keratinized squamous epithelium. It is also expressed in various squamous metaplasia, but it is down regulated in squamous dysplasia and squamous carcinoma. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Mus musculus (mouse)

Clone: KRT13/2213

Entrez Gene ID: 3860

Immunogen: Recombinant full-length human KRT13 protein

Verified AB Applications: Flow (intracellular) (verified)/IHC (FFPE) (verified)

Z-Antibody Applications: Flow, intracellular (verified)/IHC, FFPE (verified)

• Artikelnummer: BTMBNUM2659-50
• Hersteller: Biotium
• Hersteller Artikelnummer: BNUM2659-50
• Verpackungseinheit: 50 uL
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Flow Cytometry, Immunohistochemistry
• Isotyp: IgG
• Wirt: Mouse
• Konjugat: Unconjugated