Cytokeratin 6A (KRT6A) (Basal Cell Marker) (KRT6A/2368), 1mg/mL

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Description: This MAb recognizes a protein of 56 kDa, identified as cytokeratin 6A (KRT6A). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns. Cytokeratin 6A is the dominant form in epithelial tissue. Cytokeratin 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Cytokeratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express KRT6 and KRT16. KRT6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Mus musculus (mouse)

Clone: KRT6A/2368

Entrez Gene ID: 3853

Immunogen: Recombinant full-length human Cytokeratin 6A (KRT6A) protein

Verified AB Applications: Flow (intracellular) (verified)/IHC (FFPE) (verified)

Z-Antibody Applications: Flow, intracellular (verified)/IHC, FFPE (verified)

• Artikelnummer: BTMBNUM2368-50
• Hersteller: Biotium
• Hersteller Artikelnummer: BNUM2368-50
• Verpackungseinheit: 50 uL
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Flow Cytometry, Immunohistochemistry
• Isotyp: IgG2a kappa
• Wirt: Mouse
• Konjugat: Unconjugated