(D-Ala2)-GIP (human), CAS 444073-04-5

Product Description: [D-Ala2]-GIP (human) is a GIP receptor agonist. [D-Ala2]-GIP (human) improves glucose tolerance. [D-Ala2]-GIP (human) shows neuroprotective activity in MPTP-induced Parkinson's disease model. [D-Ala2]-GIP (human) also improves cognitive function and hippocampal synaptic plasticity in obese diabetic rats. [D-Ala2]-GIP (human) can be used for research of type 2 diabetes, Parkinson's disease, etc[1]

Formula: C226H338N60O66S

References: [1]Hinke SA, et al. Dipeptidyl peptidase IV-resistant [D-Ala(2)]glucose-dependent insulinotropic polypeptide (GIP) improves glucose tolerance in normal and obese diabetic rats. Diabetes. 2002 Mar;51(3):652-61./[2]Porter DW,et al. Prolonged GIP receptor activation improves cognitive function, hippocampal synaptic plasticity and glucose homeostasis in high-fat fed mice. Eur J Pharmacol. 2011 Jan 15;650(2-3):688-93./[3]Verma MK, et al. Effect of D-Ala2GIP, a stable GIP receptor agonist on MPTP-induced neuronal impairments in mice. Eur J Pharmacol. 2017 Jun 5;804:38-45.

CAS Number: 444073-04-5

Molecular Weight: 4983.60

Compound Purity: 98.17

Research Area: Metabolic Disease; Neurological Disease

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: Insulin Receptor

• Artikelnummer: MEXHY-P3247-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P3247-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK