(D)-PPA 1 (trifluoroacetate salt)

Formulation: A solid

Formal Name: D-asparaginyl-D-tyrosyl-D-seryl-D-lysyl-D-prolyl-D-threonyl-D-α-aspartyl-D-arginyl-D-glutaminyl-D-tyrosyl-D-histidyl-D-phenylalanine, trifluoroacetate salt

Purity: ≥98%

Formula Markup: C70H98N20O21 • XCF3COOH

Formula Weight: 1555,7

Shelf life (days): 1460

Notes: (D)-PPA 1 is an inhibitor of the protein-protein interaction between programmed cell death protein 1 (PD-1) and PD-1 ligand (PD-L1).{68073} It binds to the extracellular domain of PD-L1 (Kd = 0.51 µM for the recombinant human protein). (D)-PPA 1 (2 mg/kg) decreases tumor volume and improves survival in a CT26 murine colorectal cancer model.

• Artikelnummer: CAY35647-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 35647-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK
• Methode: Reinstoffe