Daminozide-d4

Formulation: A solid

Formal Name: 4-(2,2-dimethylhydrazineyl)-4-oxobutanoic-2,2,3,3-d4 acid

Purity: ≥99% deuterated forms (d1-d4)

Formula Markup: C6H8D4N2O3

Formula Weight: 164,2

Shelf life (days): 1460

Notes: Daminozide-d4 is intended for use as an internal standard for the quantification of daminozide (Item No. 12033) by GC- or LC-MS. Daminozide is an inhibitor of the 2-oxoglutarate histone lysine demethylases KDM2A, PHF8, and KDM7A (IC50s = 1.5, 0.55, and 2.1 µM, respectively) and a plant growth regulator.{21348} It is selective for KDM2A, PHF8, and KDM7A over KDM3-6 (IC50s = >100 µM for all), as well as the additional 2-oxoglutarate oxygenases FIH, EGLN1, and BBOX1 (IC50s = >100 µM for all). It reduces peduncle and internodal elongation in C. officinalis when applied at the visible bud stage at concentrations of 1,500, 3,500, or 5,000 ppm.{51391} Formulations containing daminozide have previously been used in agricultural applications to control plant growth and fruit size.

• Artikelnummer: CAY39264-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 39264-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung