DCTN2 Antibody - N-terminal region : Biotin

DCTN2 Antibody - N-terminal region : Biotin
Artikelnummer
AVIARP58450_P050-Btn
Verpackungseinheit
100μl
Hersteller
Aviva Systems Biology

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Conjugation: Biotin

Description of Target: DCTN2 is a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DCTN2

Key Reference: Camargo,L.M., (2007) Mol. Psychiatry 12 (1), 74-86

Molecular Weight: 45kDa

Peptide Sequence: Synthetic peptide located within the following region: ADPKYADLPGIARNEPDVYETSDLPEDDQAEFDAFAQELEELTSTSVEHI

Product Format: Liquid. Purified antibody supplied in 1x PBS buffer.

Protein Name: Dynactin subunit 2

Protein Size: 406

Purification: Affinity Purified

Subunit: 2
Mehr Informationen
Artikelnummer AVIARP58450_P050-Btn
Hersteller Aviva Systems Biology
Hersteller Artikelnummer ARP58450_P050-Biotin
Verpackungseinheit 100μl
Mengeneinheit STK
Reaktivität Human, Mouse (Murine), Rat (Rattus), Rabbit, Dog (Canine), Guinea Pig, Cow (Bovine), Zebrafish, Horse (Equine)
Klonalität Polyclonal
Methode Western Blotting
Human Gene ID 10540
Wirt Rabbit
Konjugat Conjugated, Biotin
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