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Den1, GST-tag Recombinant
Den1, GST-tag Recombinant
Artikelnummer
BPS81084
Verpackungseinheit
25 µg
Hersteller
BPS Bioscience
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Applications: This enzyme is active in the NEDD8-IsoPro assay. Suggested Substrate: NEDD8-AMC
Background: DEN1 (SENP8, NEDP1) is a deNEDDylase that deconjugates NEDD8 conjugates. A recent study demonstrated that DEN1 deNEDDylated the tumor suppressor breast cancer-associated protein BCA3. Full length DEN1 cleaves NEDD8-PLA2 with high efficiency.
Description: Human Den1 recombinant protein, with GST-tag, expressed in E. coli.
Format: Aqueous buffer solution
Storage Stability: Store at or below -80°C. Stable as supplied for up to 1 year when stored dessicated at -80°C.
Tags: GST-tag
Uniprot: Q96LD8
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Mendoza, H.M., et al., NEDP1, a highly conserved cysteine protease that deNEDDylates Cullins. J. Biol. Chem., 2003. 278(28):25637-43.
2. Gan?Erdene, T., et al., Identification and characterization of DEN1, a deneddylase of the ULP family. J. Biol. Chem., 2003. 278(31):.28892?900.
3. Wu, K., et al., DEN1 Is a Dual Function Protease Capable of Processing the C-Terminus of Nedd8 and Deconjugating Hyper?neddylated CUL1. J. Biol. Chem., 2003. 278(31):28882?28891.
Applications: This enzyme is active in the NEDD8-IsoPro assay. Suggested Substrate: NEDD8-AMC
Background: DEN1 (SENP8, NEDP1) is a deNEDDylase that deconjugates NEDD8 conjugates. A recent study demonstrated that DEN1 deNEDDylated the tumor suppressor breast cancer-associated protein BCA3. Full length DEN1 cleaves NEDD8-PLA2 with high efficiency.
Description: Human Den1 recombinant protein, with GST-tag, expressed in E. coli.
Format: Aqueous buffer solution
Storage Stability: Store at or below -80°C. Stable as supplied for up to 1 year when stored dessicated at -80°C.
Tags: GST-tag
Uniprot: Q96LD8
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Mendoza, H.M., et al., NEDP1, a highly conserved cysteine protease that deNEDDylates Cullins. J. Biol. Chem., 2003. 278(28):25637-43.
2. Gan?Erdene, T., et al., Identification and characterization of DEN1, a deneddylase of the ULP family. J. Biol. Chem., 2003. 278(31):.28892?900.
3. Wu, K., et al., DEN1 Is a Dual Function Protease Capable of Processing the C-Terminus of Nedd8 and Deconjugating Hyper?neddylated CUL1. J. Biol. Chem., 2003. 278(31):28882?28891.
| Artikelnummer | BPS81084 |
|---|---|
| Hersteller | BPS Bioscience |
| Hersteller Artikelnummer | 81084 |
| Green Labware | Nein |
| Verpackungseinheit | 25 µg |
| Mengeneinheit | STK |
| Produktinformation (PDF) |
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| MSDS (PDF) |
|
Immer für Sie da
Gernot Ensinger, M.Sc.
Laurent Haze
