DEPDC5 (phospho Thr1531) antibody

Application Note: WB: 1:1000-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 181

Form: Liquid

Buffer (with preservative): PBS, 150mM NaCl, 50% Glycerol, 0.02% sodium azide.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes a member of the IML1 family of proteins involved in G-protein signaling pathways. The mechanistic target of rapamycin complex 1 (mTORC1) pathway regulates cell growth by sensing the availability of nutrients. The protein encoded by this gene is a component of the GATOR1 (GAP activity toward Rags) complex which inhibits the amino acid-sensing branch of the mTORC1 pathway. Mutations in this gene are associated with autosomal dominant familial focal epilepsy with variable foci. A single nucleotide polymorphism in an intron of this gene has been associated with an increased risk of hepatocellular carcinoma in individuals with chronic hepatitis C virus infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

Uniprot ID: O75140

Antigen Species: Human

Immunogen: A synthesized peptide derived from human DEPDC5 (Accession O75140), corresponding to amino acid residues around phosphorylated Ser1530.

Purification: Purified by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns

Conjugation: Unconjugated

Full Name: DEP domain containing 5

• Artikelnummer: GTX04329-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX04329-100
• Green Labware: Nein
• Verpackungseinheit: 100 μl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Polyclonal
• Methode: Western Blotting, ELISA
• Isotyp: IgG
• Human Gene ID: 9681
• Wirt: Rabbit