Desmoglein 1 antibody (MSVA-544M) HistoMAX™

Quote the promo code SZANTIBODY when ordering to receive a 10% discount on this antibody, from October 1st to December 31st 2024. No additional discounts during the promo.

Clone Name: MSVA-544M

Light Chain: Kappa

Product Description: This antibody was validated on 76 different Normal Tissues by IHC-P.

Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

Application Note: IHC-P: 1:75-1:150. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 114

Positive Control: Tonsil: A moderate to strong desmoglein 1 immunostaining should be seen in a fraction of squamous epithelial cells.

Negative Control: Desmoglein 1 immunostaining should be absent in all non-squamous epithelial cell types.

Form: Liquid

Buffer (with preservative): 10mM PBS, 0.05% BSA (Please contact us for BSA and azide free format), 0.05% sodium azide.

Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015]

Uniprot ID: Q02413

Antigen Species: Human

Immunogen: Bovine desmoglein (desmosomal glyco protein I) from nasal epidermis.

Purification: Protein A/G purified

Conjugation: Unconjugated

Full Name: desmoglein 1

• Artikelnummer: GTX04464-S-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX04464-S-100
• Verpackungseinheit: 100 μl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG2a
• Human Gene ID: 1828
• Wirt: Mouse
• Konjugat: Unconjugated