Desmoglein 3 antibody (MSVA-543M) HistoMAX™

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Clone Name: MSVA-543M

Light Chain: Kappa

Product Description: This antibody was validated on 76 different Normal Tissues by IHC-P.

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Application Note: IHC-P: 1:75-1:150. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 108

Positive Control: Tonsil: A moderate to strong desmoglein 3 immunostaining should be seen in a fraction of squamous epithelial cells.

Negative Control: Tonsil: Desmoglein 3 immunostaining should be absent in all non-squamous epithelial cell types.

Form: Liquid

Buffer (with preservative): 10mM PBS, 0.05% BSA (Please contact us for BSA and azide free format), 0.05% sodium azide.

Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris. [provided by RefSeq, Jan 2016]

Uniprot ID: P32926

Antigen Species: Human

Immunogen: Recombinant fragment (around aa 379-491) human DSG3 protein

Purification: Protein A/G purified

Conjugation: Unconjugated

Full Name: desmoglein 3

• Artikelnummer: GTX04468-500
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX04468-500
• Verpackungseinheit: 500 μl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG1
• Human Gene ID: 1830
• Wirt: Mouse
• Konjugat: Unconjugated