iLite® ADCC Effector (V), Assay Ready Cells

iLite® ADCC Effector (V) Assay Ready Cells are based on a human T lymphocyte cell line, Jurkat (ATCC #TIB-152), and have been genetically engineered and optimized to express high levels of the low affinity Fc receptor FcRyIIIa (CD16), and the Firefly Luciferase (FL) reporter gene under the control of a proprietary chimeric promoter. The FcRyIIIa receptor responds to ligation of the Fc moiety of an antibody bound to the specific antigen on target cells by activation of the FL reporter gene. Normalization of cell counts, serum matrix effects or lysis of the effector cells by the target cells is obtained by a second reporter gene, a Renilla Luciferase reporter gene construct, under control of a constitutive promotor.

• Artikelnummer: WIEBM5001
• Hersteller: Svar Life Science / Eurodiagnostica
• Hersteller Artikelnummer: BM5001
• Verpackungseinheit: 250 µL
• Mengeneinheit: PAK