iLite® ADCC Target mTNF-alpha (-) Assay Ready Cells are based on a human embryonic kidney cell line, HEK293 (ATCC# CRL-1573), and have been genetically engineered and optimized to deplete all expression of the surface protein mTNF-alpha. The cells are for use as internal controls together with iLite® ADCC Effector (V) Assay Ready Cells and iLite® ADCC Target mTNF-alpha (+) Assay Ready Cells when measuring the ADCC activity of anti-TNF-alpha antibodies.