iLite® IFN type I FAST Assay Ready Cells are human embryonic kidney HEK293 cells (used under a license obtained from AdVec Inc) that have been genetically engineered and optimized to be responsive to type I interferon, resulting in a proportional expression of Firefly Luciferase.
This product can be used for studies of type I interferon (IFNα and IFNβ) in test samples, including human serum.
The cells also contain a Renilla Luciferase internal standardization gene under the control of a constitutive promoter that renders assay results independent of cell number and provides a means for correcting for cytotoxic effects that may be encountered in some biological samples.