Formulation: A solution in ethanol
Formal Name: N,N-dimethyl-β-alanine (10Z,13Z)-1-(9Z,12Z)-9,12-octadecadien-1-yl-10,13-nonadecadien-1-yl ester
Purity: ≥95%
Formula Markup: C42H77NO2
Formula Weight: 628,1
Shelf life (days): 1095
CAS Number: 1221271-55-1
Notes: DLin-MC2-DMA is an ionizable cationic lipid (pKa = 5.64) that has been used in the formation of lipid nanoparticles (LNPs).{54974} LNPs containing DLin-MC2-DMA and encapsulating siRNA targeting mRNA encoding mouse coagulation Factor VII (FVII) reduce hepatic levels of FVII in mice (ED50 = 0.6 mg/kg).