DLin-MC3-DMA, CAS 1224606-06-7

Formulation: A solution in ethanol

Formal Name: 4-(dimethylamino)-butanoic acid, (10Z,13Z)-1-(9Z,12Z)-9,12-octadecadien-1-yl-10,13-nonadecadien-1-yl ester

Purity: ≥95%

Formula Markup: C43H79NO2

CAS Number: 1224606-06-7

Notes: DLin-MC3-DMA is an ionizable cationic amino lipid (apparent pKa = 6.44) that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs).{54974} Administration of Factor VII siRNA in DLin-MC3-DMA-containing LNPs reduces plasma Factor VII protein levels in mice. Formulations containing DLin-MC3-DMA have been used in the development of LNPs for siRNA delivery in patients with hereditary transthyretin-mediated amyloidosis.

• Artikelnummer: CAY34364-50
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 34364-50
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK