Solubility: Soluble to 100 mM in DMSO, and to 100 mM in ethanol
Appearance: White solid
PubChem CID: 148124
Scientific Background: Docetaxel is a semi-synthetic analogue of paclitaxel differing at two positions in its chemical structure (1). It also binds and stabilizes microtubules which leads to cell cycle arrest and apoptosis (2).
References: 1. Clarke S.J., and Rivory L.P. (1999) Clin Pharmacokinet. 36(2): 99-114.2. Woodward E.J. and Twelves C. (2010) Curr. Clin Pharmacol. 5(3): 226-231.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.