Doxylamine-d5 (succinate), CAS 1216840-94-6

Formulation: A solid

Formal Name: butanedioic acid, compd. with N,N-dimethyl-2-[1-phenyl-d5-1-(2-pyridinyl)ethoxy]ethanamine

Purity: ≥95%

Formula Markup: C17H17D5N2O • C4H6O4

Formula Weight: 393,5

Shelf life (days): 1460

CAS Number: 1216840-94-6

Notes: Doxylamine-d5 is intended for use as an internal standard for the quantification of doxylamine by GC- or LC-MS. Doxylamine is an antihistamine.{66690,66691} It selectively inhibits contractions induced by histamine (Item No. 33828) over acetylcholine (ACh; Item No. 23829) in isolated guinea pig ileum (IC50s = 0.01 and 0.58 µg/ml, respectively).{66692} Doxylamine (2-4 mg/kg) protects rabbits against anaphylaxis induced by beef serum antigen.{66691} It reduces ethanol-induced deficits in behavior performance in rats when administered at a dose of 60 mg/kg.{66693} Formulations containing doxylamine have been used in the treatment of nausea and vomiting in pregnant women and insomnia.

• Artikelnummer: CAY40674-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 40674-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung