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DPP8 Assay Kit
DPP8 Assay Kit
Artikelnummer
BPS80208
Verpackungseinheit
96 rxns.
Hersteller
BPS Bioscience
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Products from BPS Bioscience require a minimum order value above 400€
Applications: Great for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
Background: Dipeptidyl peptidase-8 (DPP8) is a ubiquitously expressed serineexopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides.DPP8 shares homology and substrate recognition patterns with DPP4 and like DPP4, isthought to play a role in T-cell activation and immune function.
Contraindications: DMSO >1%, strong acids or bases, ionic detergents, high salt
Description: The Fluorogenic DPP8Assay Kit is designed to measure DPP8 activity using purified DPP8 for screening andprofiling applications. The key tothe Fluorogenic DPP8 Assay Kit is the fluorogenic substrate. Using this kit, only onesimple step on a microtiter plate is required for DPP8 reactions. The fluorometricsubstrate is incubated with a sample containing DPP8 enzyme to produce a fluorophorethat can then be measured using a fluorescence reader.
Storage Stability: At least 12 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival.
Supplied As: Supplied in a convenient 96-well format, with purified DPP8 enzyme, DPP substrate, and DPP assay buffer for 100 enzyme reactions.
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Lee, H.J. et al., J. Biol. Chem. 281 (50), 38653-38662 (2006).
2. Yu, D.M. et al., FEBS J. 273 (11), 2447-2460 (2006).Application Reference(s):Ran, Y., et al. Mol Divers . 2015 May;19(2):333-46. doi: 10.1007/s11030-015-9570-x. Scaffold-based design of xanthine as highly potent inhibitors of DPP-IV for improving glucose homeostasis in DIO mice (2015)
Applications: Great for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
Background: Dipeptidyl peptidase-8 (DPP8) is a ubiquitously expressed serineexopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides.DPP8 shares homology and substrate recognition patterns with DPP4 and like DPP4, isthought to play a role in T-cell activation and immune function.
Contraindications: DMSO >1%, strong acids or bases, ionic detergents, high salt
Description: The Fluorogenic DPP8Assay Kit is designed to measure DPP8 activity using purified DPP8 for screening andprofiling applications. The key tothe Fluorogenic DPP8 Assay Kit is the fluorogenic substrate. Using this kit, only onesimple step on a microtiter plate is required for DPP8 reactions. The fluorometricsubstrate is incubated with a sample containing DPP8 enzyme to produce a fluorophorethat can then be measured using a fluorescence reader.
Storage Stability: At least 12 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival.
Supplied As: Supplied in a convenient 96-well format, with purified DPP8 enzyme, DPP substrate, and DPP assay buffer for 100 enzyme reactions.
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Lee, H.J. et al., J. Biol. Chem. 281 (50), 38653-38662 (2006).
2. Yu, D.M. et al., FEBS J. 273 (11), 2447-2460 (2006).Application Reference(s):Ran, Y., et al. Mol Divers . 2015 May;19(2):333-46. doi: 10.1007/s11030-015-9570-x. Scaffold-based design of xanthine as highly potent inhibitors of DPP-IV for improving glucose homeostasis in DIO mice (2015)
| Artikelnummer | BPS80208 |
|---|---|
| Hersteller | BPS Bioscience |
| Hersteller Artikelnummer | 80208 |
| Green Labware | Nein |
| Verpackungseinheit | 96 rxns. |
| Mengeneinheit | PAK |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
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Gernot Ensinger, M.Sc.
Laurent Haze
