eIF2 alpha (phospho Ser51) antibody (GT1203)

Clone Name: GT1203

Application Note: WB: 1:500 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 36

Form: Liquid

Buffer (with preservative): PBS, 50% Glycerol, 0.02% Sodium azide.

Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)

Background: The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010]

Uniprot ID: P05198

Antigen Species: Human

Immunogen: A synthesized peptide derived from human Phospho-EIF2S1 (S51).

Conjugation: Unconjugated

Full Name: eukaryotic translation initiation factor 2 subunit alpha

• Artikelnummer: GTX00965-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX00965-100
• Green Labware: Nein
• Verpackungseinheit: 100 μl
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine)
• Klonalität: Recombinant
• Methode: Western Blotting
• Isotyp: IgG
• Human Gene ID: 1965
• Wirt: Rabbit