Product Description: Elemicin is an orally active alkenylbenzene widely distributed in many herbs and spices. Elemicin inhibits Stearoyl-CoA Desaturase 1 (SCD1) by metabolic activation. Elemicin has anti-influenza activities, antimicrobial, antioxidant, and antiviral activities. Elemicin and its reactive metabolite of 1′-Hydroxyelemicin can induce hepatotoxicity[1][2][3][4].
Applications: Cancer-programmed cell death
Formula: C12H16O3
References: [1]Yang XN, et al. Metabolic Activation of Elemicin Leads to the Inhibition of Stearoyl-CoA Desaturase 1. Chem Res Toxicol. 2019 Sep 10./[2]Yi-Kun Wang, et al. Role of Metabolic Activation in Elemicin-Induced Cellular Toxicity. J Agric Food Chem. 2019 Jul 24;67(29):8243-8252./[3]Xiao-Nan Yang, et al. Metabolic Activation of Elemicin Leads to the Inhibition of Stearoyl-CoA Desaturase 1. Chem Res Toxicol. 2019 Oct 21;32(10):1965-1976./[4]Ayodeji Oluwabunmi Oriola, et al. Essential Oils and Their Compounds as Potential Anti-Influenza Agents. Molecules. 2022 Nov 12;27(22):7797.
CAS Number: 487-11-6
Molecular Weight: 208.25
Compound Purity: 99.22
Research Area: Cancer; Infection
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: Bacterial;Influenza Virus;Stearoyl-CoA Desaturase (SCD)
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