Ellagic acid , CAS 476-66-4

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Biological Activity: Ellagic acid was found to partially inhibit CARM1, even at an inhibitor concentration 10-fold above the IC50 of 25 µM.

CAS Number: 476-66-4

Description: Ellagic acid, also known as TBBD, Gallogen, and Lagistase, can alter cytochrome P450 activity, and improve metabolism and clearance of xenobiotics, as well as alter immune function. It can also block methylation of arginine 17 of histone 3 (H3R17) by coactivator-associated arginine methyltransferase 1 (CARM1), or PRMT4, without significantly altering histone acetylase or DNA methyltransferase activity.

Format: A crystalline solid

Purity: ≥95% by HPLC

Solubility: Soluble in DMSO, purged with an inert gas. Solubility in DMSO is ~0.14 mg/ml.

Storage Stability: Store at or below -20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.

Biosafety Level: Not applicable (BSL-1)

References: 1. Allen, C.T., et al. Immunopharmacol. Immunotoxicol. 2003; 25(3):409-422.
2. Herber, D., et al., Cancer Lett. 2008; 269:262-268.
3. Girish, C., et al., Fundam. Clin. Pharmacol. 2008; 22:623-632.

• Artikelnummer: BPS27219
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 27219
• Green Labware: Nein
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK