Eotaxin-2 (CCL24), rat recombinant (rrEotaxin-2)

Kategorie: Cytokines

Formulation: lyophilized

Storage: -20°C

Weight: 10200 D

Purity: >97%

Description: Rat recombinant CCL24 produced in E.coli is a single, non-glycosylated polypeptide chain containing 93 amino acids and having a molecular mass of 10.2kDa. Eotaxin-2, also called MPIF2 and Ckb6, is a novel CC chemokine produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemoattracts cells expressing CCR3 including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Furthermore, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells. The mature protein, which includes C-terminal truncation, contains 78 amino acids (92 amino acids for the mouse homolog, without C-terminal truncation). CCL24 functions as a chemotactic chemokine for resting t-lymphocytes, and eosinophils. CCL24 has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. CCL24 is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line and binds to CCR3.

• Artikelnummer: BOL97433.5
• Hersteller: Biomol
• Hersteller Artikelnummer: 97433.5
• Green Labware: Nein
• Verpackungseinheit: 5 µg
• Mengeneinheit: STK
• Reaktivität: Rat (Rattus)
• Human Gene ID: 288593
• Wirt: Escherichia Coli