EP1 Receptor Polyclonal Antibody

Formulation: 500 µl peptide affinity-purified polyclonal antibody

Immunogen: Synthetic peptide from the C-terminal region of human EP1

Shelf life (days): 1095

Notes: The biological effects of PGE2 are mediated through interaction with four distinct membrane-bound G-protein coupled EP receptors: EP1, EP2, EP3, and EP4.{1422,6742} Binding of PGE2 to the EP1 receptor results in an increase in phosphatidyl inositol turnover with subsequent increase in intracellular free Ca2+.{3176,2034} Pharmacologically, EP1 receptors mediate contraction of smooth muscle.{1422} The human EP1 receptor is comprised of 402 amino acids with a molecular mass of approximately 42,000.{3176} The EP1 receptor is expressed in a variety of tissues, including the kidney, lung, and sensory neuron.{3176,2034,9050} Within the kidney, the EP1 receptor is expressed at high levels in the cortical, outer medullary, and inner medullary collecting duct.{2773}

• Artikelnummer: CAY101740-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 101740-500
• Green Labware: Nein
• Verpackungseinheit: 1 ea (500 µl)
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Polyclonal
• Methode: Immunofluorescence, Western Blotting, Immunohistochemistry
• Wirt: Rabbit