EP300 antibody (RW105)

Clone Name: RW105

Light Chain: Kappa

Application Note: WB: 1:250 - 1:500. ICC/IF: 1:50 - 1:200. IP: 1:10 - 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 264

Specificity/Sensitivity: This is specific for p300 protein. This recognizes residues 1921-2023.

Form: Liquid

Buffer (with preservative): PBS, 0.1% Sodium azide.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq]

Uniprot ID: Q09472

Antigen Species: Human

Immunogen: Fusion protein containing residues 1572-2371 of human KAT3B/p300. [UniProt# Q0947]

Purification: Protein G purified

Conjugation: Unconjugated

Full Name: E1A binding protein p300

• Artikelnummer: GTX30618-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX30618-100
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus), Primate, Various species
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunoprecipitation, Western Blotting, Immunocytochemistry, Chromatin Immunoprecipitation (ChIP), Electron microscopy (EM), Fluorescence-Activated Cell Sorting (FACS)
• Isotyp: IgG1
• Human Gene ID: 2033
• Wirt: Mouse