EPHA2 Assay Kit

Products from BPS Bioscience require a minimum order value above 400€

Applications: Useful for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.

Background: EPHA2 or ephrin type-A receptor 2 is a receptor tyrosine kinase that plays a role in a number of developmental processes, as well as tissue homeostasis and cancer, including prostate cancer. It has also been seen to promote cell motility and cancer metastasis. EphA2 regulation has been linked to lens transparency, kidney repair following renal injury, bone remodeling, and inner ear development.

Description: The EPHA2 Assay Kit is designed to measure EPHA2 activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent. 

Storage Stability: Up to 6 months when stored as recommended.

Supplied As: The EPHA2 Assay Kit comes in a convenient 96-well format, with enough purified EPHA2, Protein Tyrosine Kinase Substrate (Poly-Glu,Tyr 4:1), ATP, and kinase assay buffer for 96 enzyme reactions.

Biosafety Level: Not applicable (BSL-1)

References: 1. Walker-Daniels, J., et al. 1999. "Overexpression of the EphA2 tyrosine kinase in prostate cancer." The Prostate 41(4): 275-280.
2. Tandon, M., et al. 2011. "Emerging strategies for EphA2 receptor targeting for cancer therapeutics." Expert opinion on therapeutic targets 15(1): 31-51.

• Artikelnummer: BPS78002
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 78002
• Green Labware: Nein
• Verpackungseinheit: 96 rxns.
• Mengeneinheit: PAK