EPHB4 Kinase Assay Kit

Products from BPS Bioscience require a minimum order value above 400€

Applications: Useful for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.

Background: EPHB4 or Ephrin type-B receptor 4 is a protein and member of the receptor tyrosine kinase family. It binds to its ligand, Ephrin B2, to regulate cell adhesion and migration. EPHB4 plays a central role in heart morphogenesis, angiogenesis and blood vessel remodeling and permeability. It has also been implicated in prostate as well as breast cancer.

Description: The EPHB4 Kinase Assay Kit is designed to measure EPHB4 kinase activity for screening and profiling applications using ADP-Glo^® Kinase Assay as a detection reagent. 

Storage Stability: Up to 6 months when stored as recommended.

Supplied As: The EPHB4 Kinase Assay Kit comes in a convenient 96-well format, with enough purified recombinant EPHB4, substrate, ATP, and kinase assay buffer for 100 enzyme reactions.

Biosafety Level: Not applicable (BSL-1)

References: 1. Xia, G., et al. 2005. "EphB4 expression and biological significance in prostate cancer." Cancer Research 65(11): 4623-4632.
2. Noren, N.K., et al. 2006. "The EphB4 receptor suppresses breast cancer cell tumorigenicity through an Abl-Crk pathway." Nature Cell Biology 8(8): 815-825.

• Artikelnummer: BPS78009
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 78009
• Green Labware: Nein
• Verpackungseinheit: 96 rxns.
• Mengeneinheit: PAK