Epoxy Fluor 7, CAS 863223-43-2

Epoxy Fluor 7, CAS 863223-43-2
Artikelnummer
CAY10008610-25
Verpackungseinheit
25 mg
Hersteller
Cayman Chemical

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Formulation: A crystalline solid

Formal Name: cyano(6-methoxy-2-napthalenyl)methyl[(2,3)-3-phenyloxiranyl]methyl ester, carbonic acid

Purity: ≥98%

Formula Markup: C23H19NO5

Formula Weight: 389,4

Shelf life (days): 365

CAS Number: 863223-43-2

Notes: Soluble epoxide hydrolase (sEH) catalyzes the conversion of epoxyeicosatrienoic acids (EpETrEs) to the corresponding DiHETrEs thereby diminishing their vasodilator activity.{12607} Inhibitors of sEH may therefore have clinical utility for treating hypertension and systemic inflammation.{14065,14072} Epoxy fluor 7 is a sensitive fluorescent substrate for soluble epoxide hydrolase (sEH) that can be used to monitor the activity of both human and mouse enzymes.{14078} Hydrolysis of the substrate epoxide yields a highly fluorescent product that can be monitored at excitation and emission wavelengths of 330 and 465 nm, respectively. Epoxy fluor 7 is more stable in aqueous solution and offers about 2-fold better sensitivity than previously used colorimetric substrates such as NEPC.{14078}
Mehr Informationen
Artikelnummer CAY10008610-25
Hersteller Cayman Chemical
Hersteller Artikelnummer 10008610-25
Green Labware Nein
Verpackungseinheit 25 mg
Mengeneinheit STK
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