ERO1LB Polyclonal Antibody, Rabbit

ERO1LB Polyclonal Antibody, Rabbit
Artikelnummer
ELSE-AB-92546-200
Verpackungseinheit
200 µl
Hersteller
Elabscience Biotechnology

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Abbreviation: ERO1LB

Target Synonym: ERO1B;ERO1LB;Ero1beta

Conjugation: Unconjugated

UNIProt ID: Q86YB8

Background: Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Other protein disulfide isomerase family members can also be reoxidized, but at lower rates compared to P4HB, including PDIA2 (50% of P4HB reoxidation rate, as well as PDIA3, PDIA4, PDIA6 and NXNDC12 (<10%. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS in the cell. May be involved in oxidative proinsulin folding in pancreatic cells, hence may play a role in glucose homeostasis.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human ERO1LB

Dilution: WB 1:500-1:2000
Mehr Informationen
Artikelnummer ELSE-AB-92546-200
Hersteller Elabscience Biotechnology
Hersteller Artikelnummer ELA-E-AB-92546-200
Green Labware Nein
Verpackungseinheit 200 µl
Mengeneinheit STK
Reaktivität Human, Mouse (Murine)
Klonalität Polyclonal
Methode Western Blotting
Isotyp IgG
Wirt Rabbit
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