Fbx32/FBOX32 Polyclonal Antibody, Rabbit

Abbreviation: Fbx32/FBOX32

Target Synonym: FBXO32;Fbx32;MAFbx

Conjugation: Unconjugated

UNIProt ID: Q969P5

Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human Fbx32/FBOX32

Dilution: WB 1:500-1:1000,IF 1:50-1:200

• Artikelnummer: ELSE-AB-93393-60
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-E-AB-93393-60
• Green Labware: Nein
• Verpackungseinheit: 60 µl
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine)
• Klonalität: Polyclonal
• Methode: Immunofluorescence, Western Blotting
• Isotyp: IgG
• Wirt: Rabbit