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FcRL5/Firefly Luciferase RPMI 8226 Cell Line
FcRL5/Firefly Luciferase RPMI 8226 Cell Line
Artikelnummer
BPS78378
Verpackungseinheit
2 vials
Hersteller
BPS Bioscience
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Products from BPS Bioscience require a minimum order value above 400€
Applications: Use as target cells for anti-FcRL5 CAR T cells, anti-FcRL5 ADC, and bi-specific antibodies.
Background: FcRL5 is a single-pass type 1 membrane protein which contains 8 immunoglobulin-like C2-type domains. FcRL5 may be involved in B cell development and lymphomagenesis. Moreover, it is enriched in malignant plasma cells of patients diagnosed with multiple myeloma, and is an attractive target for antibody-drug conjugates (ADC) and anti-FcRL5 CAR T cells. RPMI 8226 cells are human B cells isolated from a plasmacytoma/myeloma patient.
Description: Recombinant RPMI 8226 cells constitutively expressing firefly (Photinus pyralis) luciferase (BPS Bioscience #79834) have also been engineered to constitutively express the full length human FcRL5 (Fc Receptor Like 5, also known as CD307, ref. seq. NM_031281).
Host Cell Line: RPMI 8226
Mycoplasma Testing: The cell line has been screened to confirm the absence of Mycoplasma species.
Storage Stability: Cells are shipped in dry ice and should immediately be thawed or stored in liquid nitrogen upon receipt. Do not use a -80°C freezer for long term storage.
Supplied As: Each vial contains 2 x 106 cells in 1 ml of cell freezing medium (BPS Bioscience, #79796)
Uniprot: Q96RD9
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: BSL-1
Applications: Use as target cells for anti-FcRL5 CAR T cells, anti-FcRL5 ADC, and bi-specific antibodies.
Background: FcRL5 is a single-pass type 1 membrane protein which contains 8 immunoglobulin-like C2-type domains. FcRL5 may be involved in B cell development and lymphomagenesis. Moreover, it is enriched in malignant plasma cells of patients diagnosed with multiple myeloma, and is an attractive target for antibody-drug conjugates (ADC) and anti-FcRL5 CAR T cells. RPMI 8226 cells are human B cells isolated from a plasmacytoma/myeloma patient.
Description: Recombinant RPMI 8226 cells constitutively expressing firefly (Photinus pyralis) luciferase (BPS Bioscience #79834) have also been engineered to constitutively express the full length human FcRL5 (Fc Receptor Like 5, also known as CD307, ref. seq. NM_031281).
Host Cell Line: RPMI 8226
Mycoplasma Testing: The cell line has been screened to confirm the absence of Mycoplasma species.
Storage Stability: Cells are shipped in dry ice and should immediately be thawed or stored in liquid nitrogen upon receipt. Do not use a -80°C freezer for long term storage.
Supplied As: Each vial contains 2 x 106 cells in 1 ml of cell freezing medium (BPS Bioscience, #79796)
Uniprot: Q96RD9
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: BSL-1
| Artikelnummer | BPS78378 |
|---|---|
| Hersteller | BPS Bioscience |
| Hersteller Artikelnummer | 78378 |
| Verpackungseinheit | 2 vials |
| Mengeneinheit | PAK |
| Wirt | Human |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
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