(+)-Fenfluramine (hydrochloride), CAS 3239-45-0

Formulation: A crystalline solid

Formal Name: N-ethyl-α-methyl-3-(trifluoromethyl)-benzeneethanamine, monohydrochloride

Purity: ≥95%

Formula Markup: C12H16F3N • HCl

Formula Weight: 267,7

Shelf life (days): 730

CAS Number: 3239-45-0

Notes: (+)-Fenfluramine is an agonist of the serotonin (5-HT) receptor subtypes 5-HT2B and 5-HT2C.{51800} It induces serotonin release from superfused midbrain synaptosome preparations isolated from wild-type mice, but not 5-HT2B-/- mice, when used at concentrations of 0.5 or 1 µM. (+)-Fenfluramine (3 or 10 mg/kg) reduces food intake in starved wild-type mice but not in starved 5-HT2B-/- mice. It reduces body weight gain in wild-type mice when infused at a dose of 2.5 mg/kg per day for 35 days. Formulations containing (+)-fenfluramine were previously used in the treatment of obesity.

• Artikelnummer: CAY39830-100
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 39830-100
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK