Ferroptosis Inducer 24, CAS 28657-88-7

Formulation: A solid

Formal Name: 3-phenyl-2-propenoic acid, 2-(1H-indol-3-yl)ethyl ester

Purity: ≥95%

Formula Markup: C19H17NO2

Formula Weight: 291,3

Shelf life (days): 1460

CAS Number: 28657-88-7

Notes: Ferroptosis inducer 24 is an inducer of ferroptosis.{51790} It inhibits glutathione peroxidase 4 (GPX4) by 30-35% when used at a concentration of 50 µM. Ferroptosis inducer 24 (10 µM) increases the levels of heme oxygenase-1 (HO-1) in MDA-MB-231 triple-negative breast cancer cells, as well as increases the levels of bilirubin formed by HO-1 in MDA-MB-231 cell lysates. It reduces the viability of, as well as increases the levels of oxidized lipids, decreases the levels of IL-6 and glutathione (GST), and disrupts the mitochondrial membrane potential in, MDA-MB-231 cancer cells when used at a concentration of 50 µM. Ferroptosis inducer 24 also increases the levels of reactive oxygen species (ROS) in a time-dependent manner.

• Artikelnummer: CAY41201-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 41201-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK