FGFR2, DEL (429-430), His-Tag (Dephosphorylated) Recombinant

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Encompassing Amino Acids: 400- 821(end), with deletion at 429-430

Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Assay Conditions: Assay was done according to BPS Catalog#79502 with a FGFR2 titration range of 0 ng/rxn-500 ng/rxn.

Description: Human FGFR2, also known as Fibroblast growth factor receptor 2, Keratinocyte growth factor receptor, BBDS, BEK, BFR-1 and CD332, GenBank Accession No. NM_000141, a.a. 400-821(end), with deletion at 429-430, with C-terminal His-tag, expressed in an Sf9 infected baculovirus expression system. MW = 52 kDa. This protein was isolated from a co-expression with PTP1B. Percentage of phosphorylation ≤ 10%.

Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20, 100 mM Imidazole, 3 mM DTT and 20% glycerol.

Genbank: NM_000141

Storage Stability: At least 6 months at -80°C.

Supplied As: Aqueous buffer solution.

Tags: C-terminal His-tag

Uniprot: P21802

Warnings: Avoid freeze/thaw cycles.

Biosafety Level: Not applicable (BSL-1)

References: 1. Holtrich, U. et al., Proc. Nat. Acad. Sci. (1991); 88:10411-10415.
2. Roidl, A. et al., Clin Cancer Res. (2009 Mar 15); 15(6):2058-66.

• Artikelnummer: BPS100356
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 100356
• Green Labware: Nein
• Verpackungseinheit: 10 µg
• Mengeneinheit: STK