1-Boc-azetidine-3-carboxylic acid, CAS 142253-55-2

Product Description: 1-Boc-azetidine-3-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-Boc-azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2]
Applications: Cancer-programmed cell death

Formula: C9H15NO4

References: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337./[2]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

CAS Number: 142253-55-2

Molecular Weight: 201.22

Compound Purity: 98.0

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Linker;PROTAC Linkers

• Artikelnummer: MEXHY-40141-1G
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-40141-1G
• Green Labware: Nein
• Verpackungseinheit: 1 g
• Mengeneinheit: STK