Ald-CH2-PEG3-azide, CAS 1002342-83-7

Product Description: Ald-CH2-PEG3-azide is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Ald-CH2-PEG3-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Ald-CH2-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Applications: Cancer-programmed cell death

Formula: C8H15N3O4

References: [1]Harold L. Kohn , et al. Acylhydrazone-based cleavable linkers. WO2010014236A2.

CAS Number: 1002342-83-7

Molecular Weight: 217.22

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Linker;PROTAC Linkers

• Artikelnummer: MEXHY-130144-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-130144-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK