Aminooxy-PEG2-azide, CAS 1043426-13-6

Product Description: Aminooxy-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Aminooxy-PEG2-azide is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2]. Aminooxy-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Applications: Cancer-programmed cell death

Formula: C6H14N4O3

References: [1]H. Tetsuo Uyeda, et al. Synthesis of surface ligands to prepare hydrophilic and biologically compatible quantum dots. doi: 10.1117/12.590494./[2]Song, Ho Young, et al. Pyrrolobenzodiazepine dimer precursor and ligand-linker conjugate compound thereof.

CAS Number: 1043426-13-6

Molecular Weight: 190.20

Compound Purity: 96.0

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: ADC Linker;PROTAC Linkers

• Artikelnummer: MEXHY-113931-50
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-113931-50
• Green Labware: Nein
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK