Product Description: Aminooxy-PEG4-alcohol is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Aminooxy-PEG4-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].
Applications: Cancer-programmed cell death
Formula: C8H19NO5
References: [1]Heather D. Maynard, et al. Method of creating hydrogels through oxime bond formation. US20150202305A1./[2]Murray BS, et al. Reactive thermoresponsive copolymer scaffolds. Chem Commun (Camb). 2010 Dec 7;46(45):8651-3.